In lab experiments, reducing alpha-synuclein, a protein, made layers of human brain blood-vessel cells leakier; suppressing an enzyme returned leakage to normal.In lab experiments, reducing alpha-synuclein, a protein, made layers of human brain blood-vessel cells leakier; suppressing an enzyme returned leakage to normal.
In CamCAN, adding brain-shape measures cut average age-prediction errors from 6.04 to 4.71 years compared with an anatomy-based model.In CamCAN, adding brain-shape measures cut average age-prediction errors from 6.04 to 4.71 years compared with an anatomy-based model.
Across 12 cohorts, type 2 diabetes was linked to a brain age gap 1.73 years higher than in people without diabetes.Across 12 cohorts, type 2 diabetes was linked to a brain age gap 1.73 years higher than in people without diabetes.