4 papers1 finding
NfL
upin humans1
NfL is associated with ventricular enlargement in humans.
“NfL levels were significantly associated with neurodegeneration, evidenced by reduced brain tissue volume in key regions (Figure 2a) and with ventricular enlargement”
Humansnon-dementedbrainn = 202
AAIC 2025 abstractDec 23, 2025
The gap between scan-estimated and actual age exceeded age-matched controls by 7.64 years in schizophrenia and 7.61 years in frontotemporal dementia.The gap between scan-estimated and actual age exceeded age-matched controls by 7.64 years in schizophrenia and 7.61 years in frontotemporal dementia.
Long-lived African turquoise killifish show ventricular enlargement, fibrosis, and reduced myocardial density with age rather than typical cardiomyocyte hypertrophy.Long-lived African turquoise killifish show ventricular enlargement, fibrosis, and reduced myocardial density with age rather than typical cardiomyocyte hypertrophy.