Chronic substance use disorder

Disease1 paper1 finding

  • Humans1

Associations

1

Brain-predicted age difference

upin humans1

1 study
  1. Chronic substance use disorder is associated with brain-predicted age difference in humans (+2.91 years).

    HumansCompared with age-matched controls after age-bias correctionbrain

    Brain age estimates were higher across six disorders · Psychological medicine · 7 Oct 2026

Brain-predicted age difference →

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Psychological MedicineHumans

Brain age estimates were higher across six disorders

The gap between scan-estimated and actual age exceeded age-matched controls by 7.64 years in schizophrenia and 7.61 years in frontotemporal dementia.The gap between scan-estimated and actual age exceeded age-matched controls by 7.64 years in schizophrenia and 7.61 years in frontotemporal dementia.