Brain tissue volume

3 papers study it18 more mention it2 findings

Humans3

Upstream

1

White matter hyperintensity volume

mediatesin humans1

1 study

White matter hyperintensity volume mediates brain tissue volume in humans.
“Notably, the association between NfL and neurodegeneration was no longer significant after adjusting for WMH, underscoring WMH as a critical mediator.”
Humansnon-dementedbrainn = 202
Plasma Neurofilament Light Links to Brain Tissue Loss, Ventricular Enlargement, and Elevated White Matter Hyperintensities
AAIC 2025 abstractDec 23, 2025

More on White matter hyperintensity volume

Associations

1

NfL

downin humans1

1 study

NfL is associated with brain tissue volume in humans.
“NfL levels were significantly associated with neurodegeneration, evidenced by reduced brain tissue volume in key regions”
Humansnon-dementedbrainn = 202
Plasma Neurofilament Light Links to Brain Tissue Loss, Ventricular Enlargement, and Elevated White Matter Hyperintensities
AAIC 2025 abstractDec 23, 2025

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4 papers in 12 months

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AAIC 2025 AbstractDec 25

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AAIC 2025 AbstractDec 25

Plasma Neurofilament Light Links to Brain Tissue Loss, Ventricular Enlargement, and Elevated White Matter Hyperintensities

Cohort study of 202 peopleWhite matter hyperintensities

AAIC 2025 AbstractDec 23

Plasma Neurofilament Light Links to Brain Tissue Loss, Ventricular Enlargement, and Elevated White Matter Hyperintensities

Cohort study of 202 peopleNfL

Quantitative Imaging in Medicine and SurgeryMay 19

Exploring the relationship between larmor-frequency electrical conductivity, diffusivity, and tissue volume in the aging brain

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Amplitude of Intracranial Induced Electric Fields Does Not Linearly Decrease with Age: A Computational Study of Anatomical Effects in Adults

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The Journals of Gerontology, Series AJan 8

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Neurobiology of DiseaseFeb 16

Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage

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