triglyceride-to-HDL ratio

Biomarker

8 papers4 findings

  • Human trial1
  • Humans5
  • Animals1
  • In silico1

Interventions

2

Mediterranean diet

downin rats1

1 study
  1. Mediterranean diet decreases triglyceride-to-HDL ratio in rats (p=0.01).

    “Regardless of sex, the triglyceride: HDL was higher in the WD group compared to the MeDi (p=0.02), WD to MeDi (p=0.01), and WD + MeDi-FMT (p=0.02).”

    Animalsin rats fed Western diet8 months

    Diet and Fecal Microbiota Transplantation Modulates Measurements of Cardiometabolic Health in Aging Animals: Preliminary Results

    AHA Scientific Sessions 2025 abstract3 Nov 2025

More on Mediterranean diet

Fecal microbiota transplantation

downin rats1

1 study
  1. Fecal microbiota transplantation decreases triglyceride-to-HDL ratio in rats (p=0.02).

    “Regardless of sex, the triglyceride: HDL was higher in the WD group compared to the MeDi (p=0.02), WD to MeDi (p=0.01), and WD + MeDi-FMT (p=0.02).”

    Animalsin rats fed Western diet8 months

    Diet and Fecal Microbiota Transplantation Modulates Measurements of Cardiometabolic Health in Aging Animals: Preliminary Results

    AHA Scientific Sessions 2025 abstract3 Nov 2025

More on Fecal microbiota transplantation

Associations

2

Framingham risk score

upin humans1

1 study
  1. triglyceride-to-HDL ratio is associated with Framingham risk score in humans (ρ = 0.30, p < 0.001).

    “TG/HDL ratio (ρ = 0.30, p < 0.001) showed moderate positive correlation with the FRS.”

    HumansNHANES 2017-2020

    Performance of Insulin Resistance Markers in Predicting 10-Year Cardiovascular Risk Using the Framingham Score: An NHANES-Based Study

    ADA Scientific Sessions 2026 abstract5 Jun 2026

More on Framingham risk score

Cardiovascular risk

upin humans1OR 1.35

1 study
  1. triglyceride-to-HDL ratio is associated with cardiovascular risk in humans (OR 1.35 (95% CI 1.22-1.50)).

    “TG/HDL: OR = 1.35; 95% CI: 1.22-1.50; p < 0.001 for both”

    HumansNHANES 2017-2020

    Performance of Insulin Resistance Markers in Predicting 10-Year Cardiovascular Risk Using the Framingham Score: An NHANES-Based Study

    ADA Scientific Sessions 2026 abstract5 Jun 2026

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