SIRT1 deacetylase activity

2 papers study it14 more mention it

Cells2

Latest

3 papers in 12 months

Aging CellMay 2

SIRT1 Downregulation by Advanced Glycation End Products Activates RANKL-Dependent Osteoclast Signaling and Drives Chondrocyte Senescence During Osteoarthritis Development

Experiments in miceAGE–RAGE signaling

ZenodoApr 28

SIRT1 Activation Combined with NAD+ Precursor Supplementation

PreprintNAD+ precursors

EMBO ReportsNov 11

Meiotic cohesion requires Sirt1 and preserving its activity in aging oocytes reduces missegregation

Experiments in fliesInterventions

bioRxivMar 31

Meiotic cohesion requires Sirt1 and preserving its activity in aging oocytes reduces missegregation

Preprint: experiments in fliesInterventions

Gastroenterology ReportMay 17

ELMO1 ameliorates intestinal epithelial cellular senescence via SIRT1/p65 signaling in inflammatory bowel disease-related fibrosis

Study in peopleInflammatory bowel disease

Aging and DiseaseFeb 1

Isthmin-1 Improves Aging-Related Cardiac Dysfunction in Mice through Enhancing Glycolysis and SIRT1 Deacetylase Activity

Experiments in miceInterventions

Science China Life SciencesMay 29

Insulin-like growth factor binding proteins 7 prevents dental pulp-derived mesenchymal stem cell senescence via metabolic downregulation of p21

Experiments in cellsOxidative phosphorylation

Cell ReportsNov 25

LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity

Experiments in animalsMechanisms

COPDJul 30

Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence

Experiments in animalsInterventions

Research SquareJul 22

Nicotinamide mononucleotide treatment increases NAD+ levels in an iPSC Model of Parkinson’s Disease but does not impact sirtuin activity

Preprint: experiments in human cellsNicotinamide mononucleotide