SIRT1 or SIRT3 deacetylase activity

Biomarker

1 paper studies it1 finding

  • Cells1

Interventions

1

Nicotinamide mononucleotide

no changein human cells1

1 study
  1. Nicotinamide mononucleotide has no effect on SIRT1 or SIRT3 deacetylase activity in human cells.

    “but NMN had no impact on deacetylase activity of SIRT 1 or 3.”

    CellsPD iPSC-derived dopaminergic neurons

    Nicotinamide mononucleotide treatment increases NAD+ levels in an iPSC Model of Parkinson’s Disease but does not impact sirtuin activity

    Research SquarePreprint

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