CDKN1A transcription
2 papers study it5 more mention it2 findings
- Animals1
- Cells1
Upstream
2PDRG1
downin human cells1
1 study
PDRG1
downin human cells1
PDRG1 decreases CDKN1A transcription in human cells.
“Mechanistically, PDRG1 directly interacted with EZH2, increased H3K27me3 enrichment at the p21 promoter, and suppressed p21 transcription.”
Cellshepatocellular carcinoma cell
International journal of biological sciences
IGFBP7
downin cells1
1 study
IGFBP7
downin cells1
IGFBP7 decreases CDKN1A transcription in cells.
“IGFBP7 in preventing DPSC senescence via the metabolism-induced deacetylation of H3K36ac and reduction of p21 transcription”
Cellsdental pulp-derived mesenchymal stem cell
Science China. Life sciences
Latest
2 papers in 12 monthsNature Cell Biology
Transcription-independent induction of rapid-onset senescence is integral to healing
Experiments in miceCellular senescence
International Journal of Biological Sciences
Identification of a Novel PDRG1-EZH2-p21 Pathway Controlling Senescence and Tumor Progression in Hepatocellular Carcinoma
Experiments in animalsCellular senescence
Science China Life Sciences
RIG-I-driven CDKN1A stabilization reinforces cellular senescence
Experiments in human cellsCellular senescence
Science China Life Sciences
Insulin-like growth factor binding proteins 7 prevents dental pulp-derived mesenchymal stem cell senescence via metabolic downregulation of p21
Experiments in cellsOxidative phosphorylation
Aging
Cdkn1a transcript variant 2 is a marker of aging and cellular senescence
Experiments in miceCellular senescence
Biology of Reproduction
Contribution of senescence in human endometrial stromal cells during proliferative phase to embryo receptivity†
Experiments in cellsMechanisms