There are 4 papers on serum pro-inflammatory cytokine levels in aging research: 1 trial in people, 3 in animals.
4 papers study it1 more mentions it4 findings
- Human trial1
- Animals3
Interventions
3Xanthurenic acid
downin mice1
1 study
Xanthurenic acid
downin mice1
Xanthurenic acid decreases serum pro-inflammatory cytokine levels in mice.
“XA treatment decreased pro-inflammatory cytokines (TNF-α, IL-1, IFN-γ, IL-6) in serum.”
Animals
XANTHURENIC ACID (XA) TREATMENT IMPROVES OVERALL HEALTH IN AGED MICE
GSA 2024 abstract
Dexmedetomidine
downin humans1
1 study
Dexmedetomidine
downin humans1
Dexmedetomidine decreases serum pro-inflammatory cytokine levels in humans (medium- and high-dose groups on day 2 after surgery, compared with baseline).
“On D2, TNF-α, L-1β and IL-6 recovered their baseline levels in medium- and high-dose DEX groups (P > 0.05) but remained elevated in the other two groups.”
Human trialmedium- and high-dose groups on day 2 after surgery, compared with baselinemedium and high maintenance doses
Nan fang yi ke da xue xue bao = Journal of Southern Medical University
Pioglitazone
downin mice1
1 study
Pioglitazone
downin mice1
Pioglitazone decreases serum pro-inflammatory cytokine levels in mice (sepsis induced by intravenous injection of a lethal dose of Escherichia coli).
“lowered serum pro-inflammatory cytokines (TNF-α, IL-12, IFN-γ)”
Animalssepsis induced by intravenous injection of a lethal dose of Escherichia coli
Innate immunity
Upstream
1fat-1
downin mice1
1 study
fat-1
downin mice1
fat-1 decreases serum pro-inflammatory cytokine levels in mice.
“Serum pro-inflammatory markers, such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, and IL-6 were found lower in Fat-1 mice, as compared to that of WT mice.”
Animalsserum5 months
Oxidative medicine and cellular longevity