Proliferation
Biomarker1 paper1 finding
- Cells1
Interventions
1Serum
upin rat cells1Very low certainty
1 study
Serum
upin rat cells1Very low certainty
Serum increases proliferation in rat cells.
Cellsin older DPSCs
Serum-induced recovery of proliferative capacity and differentiation potential in aged dental pulp stem cells · Stem cells translational medicine · 18 Aug 2026
Latest
157Young-donor cell packages improved limb repair in rats
In a rat experiment, cell-released packages from young donors had stronger tissue-repair effects than those from older donors after blood supply was…In a rat experiment, cell-released packages from young donors had stronger tissue-repair effects than those from older donors after blood supply was restricted.
Exercise-Induced Activation of IGF-1/mTOR Signaling and Hippocampal BDNF/PGC-1α Expression Reverses Age-Related Motor Decline
SASP factors drive growth of altered cancer cells in culture
Using a microarray platform, researchers identified shared growth drivers in breast and lung cancer cells that required cellular alterations to…Using a microarray platform, researchers identified shared growth drivers in breast and lung cancer cells that required cellular alterations to promote proliferation.
Direct conversion to neural stem cells de-ages human blood cells
Converted cells preserved around 13% and 5% of original donor age at low and high passages, respectively, through a protracted de-aging process.Converted cells preserved around 13% and 5% of original donor age at low and high passages, respectively, through a protracted de-aging process.
Unraveling skeletal muscle senescence in an in vitro cell culture model
Calcium overload impairs muscle regeneration by driving sustained NFAT signaling
Inhibiting NFAT restored myoblast differentiation in culture and improved myofiber repair in injured mice.Inhibiting NFAT restored myoblast differentiation in culture and improved myofiber repair in injured mice.
Aged human muscle secretes an enzyme that impairs stem cell maintenance
Profiling conditioned media revealed that altered sphingolipid signaling reduces muscle stem cell pools in human cell cultures.Profiling conditioned media revealed that altered sphingolipid signaling reduces muscle stem cell pools in human cell cultures.
Senescent CD4 T cells drive age-associated autoimmunity in mice and humans
Targeting senescent immune cells with fisetin or ruxolitinib reduced disease features and protected mice against autoimmune peripheral nerve damage.Targeting senescent immune cells with fisetin or ruxolitinib reduced disease features and protected mice against autoimmune peripheral nerve damage.