Plasma ADRD biomarkers

Biomarker1 paper2 findings

  • Human trial1

Interventions

2

Marine omega-3 fatty acids

no changein humans1Moderate certainty

1 study
  1. Marine omega-3 fatty acids have no effect on plasma ADRD biomarkers in humans.

    Human trialover 4 yearsplasma1 g/day4 yearsn = 929

    Effects of long-term daily supplementation with vitamin D3 and marine omega-3 fatty acids on change in ADRD biomarkers: A secondary analysis of a randomized clinical trial · Alzheimer's & dementia (New York, N. Y.) · 14 Sep 2026

Marine omega-3 fatty acids →

Cholecalciferol

no changein humans1Moderate certainty

1 study
  1. Cholecalciferol has no effect on plasma ADRD biomarkers in humans.

    Human trialover 4 yearsplasma2000 IU/day4 yearsn = 929

    Effects of long-term daily supplementation with vitamin D3 and marine omega-3 fatty acids on change in ADRD biomarkers: A secondary analysis of a randomized clinical trial · Alzheimer's & dementia (New York, N. Y.) · 14 Sep 2026

Cholecalciferol →

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