Plasma ADRD biomarkers
Biomarker1 paper2 findings
- Human trial1
Interventions
2Marine omega-3 fatty acids
no changein humans1Moderate certainty
1 study
Marine omega-3 fatty acids
no changein humans1Moderate certainty
Marine omega-3 fatty acids have no effect on plasma ADRD biomarkers in humans.
Human trialover 4 yearsplasma1 g/day4 yearsn = 929
Effects of long-term daily supplementation with vitamin D3 and marine omega-3 fatty acids on change in ADRD biomarkers: A secondary analysis of a randomized clinical trial · Alzheimer's & dementia (New York, N. Y.) · 14 Sep 2026
Cholecalciferol
no changein humans1Moderate certainty
1 study
Cholecalciferol
no changein humans1Moderate certainty
Cholecalciferol has no effect on plasma ADRD biomarkers in humans.
Human trialover 4 yearsplasma2000 IU/day4 yearsn = 929
Effects of long-term daily supplementation with vitamin D3 and marine omega-3 fatty acids on change in ADRD biomarkers: A secondary analysis of a randomized clinical trial · Alzheimer's & dementia (New York, N. Y.) · 14 Sep 2026