Marine omega-3 fatty acids

1. Marine omega-3 fatty acids decrease glial fibrillary acidic protein in humans (-12.4% (95% CI: -21.5% to -2.2%)).

   Human trialin Black participantsplasma1 g/day4 years

   Effects of long-term daily supplementation with vitamin D3 and marine omega-3 fatty acids on change in ADRD biomarkers: A secondary analysis of a randomized clinical trial · Alzheimer's & dementia (New York, N. Y.) · 14 Sep 2026

Glial fibrillary acidic protein →

1. Marine omega-3 fatty acids have no effect on plasma ADRD biomarkers in humans.

   Human trialover 4 yearsplasma1 g/day4 yearsn = 929

   Effects of long-term daily supplementation with vitamin D3 and marine omega-3 fatty acids on change in ADRD biomarkers: A secondary analysis of a randomized clinical trial · Alzheimer's & dementia (New York, N. Y.) · 14 Sep 2026

Plasma ADRD biomarkers →