ADHD polygenic risk score
Biomarker1 paper1 finding
- Humans1
Associations
1Incident mild cognitive impairment or dementia
upin humans1HR 1.35
1 study
Incident mild cognitive impairment or dementia
upin humans1HR 1.35
ADHD polygenic risk score is associated with incident mild cognitive impairment or dementia in humans (HR 1.35, 95% CI 1.25–1.46).
HumansHighest versus lowest ADHD PRS quintileMean follow-up 10.26 yearsn = 187,341
Attention-deficit/hyperactivity disorder linked to impaired thinking · JAMA psychiatry · 7 Oct 2026
Latest
1JAMA PsychiatryHumans
Attention-deficit/hyperactivity disorder linked to impaired thinking
Cognitive impairment developed in 6.7% of participants with the disorder, compared with 3.4% without it, in a cohort of adults aged 50 and older.Cognitive impairment developed in 6.7% of participants with the disorder, compared with 3.4% without it, in a cohort of adults aged 50 and older.