Papers on p62/SQSTM1
50 papers2 new in 30 days
Thursday, October 22
Friday, September 25
Thursday, April 16
Sunday, December 22
Development
Deficient autophagy in epithelial stem cells drives aging in the freshwater cnidarian Hydra
Experiments in hydraAutophagy
Friday, December 13
Nature Communications
The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy
Experiments in wormsInterventions
Saturday, November 23
Nutrients
Exercise Mitigates the Loss of Muscle Mass by Attenuating the Activation of Autophagy during Severe Energy Deficit
Non-randomized trial in peopleExercise
Thursday, July 25
Cell Reports
Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila
Experiments in fliesInterventions
Tuesday, February 12
Journal of Cellular Physiology
P62 deficiency shifts mesenchymal/stromal stem cell commitment toward adipogenesis and disrupts bone marrow homeostasis in aged mice
Experiments in miceSQSTM1
Tuesday, February 5
Osteoarthritis and Cartilage
Pharmacological inhibition of mTORC1 but not mTORC2 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism through Akt and autophagy induction
Experiments in human cellsmTOR inhibitors
Wednesday, December 12
Stem Cell Research & Therapy
A pH probe inhibits senescence in mesenchymal stem cells
Experiments in rat cellsInterventions
Thursday, September 27
Wednesday, August 29
Aging
p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model
Experiments in animalsInterventions
Monday, September 11
Osteoarthritis and Cartilage
Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction
Experiments in human cellsmTOR signaling
Monday, February 6
Aging
Impact of resistance training on the autophagy-inflammation-apoptosis crosstalk in elderly subjects
Randomized trial in 26 peopleResistance training
Saturday, August 6
Journal of Cachexia, Sarcopenia and Muscle
p62/SQSTM1 but not LC3 is accumulated in sarcopenic muscle of mice
Experiments in miceSQSTM1
Saturday, May 28
Biogerontology
Cellular degradation activity is maintained during aging in long-living queen bees
Experiments in honeybeesMechanisms
Wednesday, May 11
Journal of Huntington's Disease
AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington's Disease
Experiments in fliesHuntington's disease
Thursday, March 3
Age
Effects of aerobic training on markers of autophagy in the elderly
Randomized trial in 29 peopleAerobic exercise
Friday, December 19
Cell Death and Differentiation
Spermidine induces autophagy by inhibiting the acetyltransferase EP300
Experiments in human cellsAutophagy