P53 activation
1 paper
- Animals1
Latest
8 in 12 monthsAging and Disease
Context-Dependent Roles of p53 in Cellular Senescence and Fibrosis
ReviewCellular senescence
International Immunopharmacology
Dietary N-acetylneuraminic acid maintains intestinal homeostasis and protects against aging- and inflammation-associated colonic dysfunction
Experiments in miceGut and microbiome
Histology and Histopathology
Caloric restriction attenuates age-related liver and kidney alterations in mice: Histological evidence
Experiments in 5 miceDietary restriction
American Journal of Respiratory and Critical Care Medicine
Cellular profiling identifies an early profibrotic alveolar type 2 cell signature in lung fibrosis
Experiments in miceLung
Cardiovascular Research
Integrative transcriptomic profiling links telomere dysfunction to cGAS-STING activation in heart failure signatures in mice and humans
Experiments in animalsMechanisms
Nature Cell Biology
p53 increases phospholipid headgroup scavenging in senescence
Experiments in cellsMechanisms
Cancer Research
Cortactin Suppresses mTOR-Dependent Senescence in Circulating Tumor Cells
Experiments in animalsInterventions
Cell Death & Disease
Pharmacological activation of p53 induces dose-dependent changes in endothelial cell fate during angiogenic sprouting
Experiments in animalsMechanisms
Nature Communications
Adipocyte FMO3-derived TMAO induces WAT dysfunction and metabolic disorders by promoting inflammasome activation in ageing
Experiments in miceNLRP3 inflammasome
Journal of Diabetes
Taurine Alleviates Pancreatic β-Cell Senescence by Inhibition of p53 Pathway
Experiments in mouse cellsInterventions