Free Radical Biology & Medicine
The role of metabolic stress, xanthine oxidase, NOX2, and redox-related signalling in regulating ACE2 protein expression in exercising human skeletal muscle
Non-randomized trial in 11 peopleMuscle
Papers on P47PHOX
23 papers
Tuesday, March 10
Friday, October 17
Preprints.org
Fluorescence Lifetime Imaging Microscopy Reveals Metabolic Changes in Aging Lacrimal Gland Suggestive of Increased Inflammation and Oxidative Stress
Preprint: experiments in animalsOxidative phosphorylation
Thursday, August 14
Free Radical Biology & Medicine
Urolithin A protects against domoic acid-induced cognitive deficits via promoting estrogen receptor-α-mediated mitochondrial biogenesis signaling in mice
Experiments in miceUrolithin A
Monday, May 8
Tuesday, November 22
Biochimica et Biophysica Acta General Subjects
Interplay between obesity and aging on myocardial geometry and function: Role of leptin-STAT3-stress signaling
Experiments in miceJNK signaling
Sunday, December 19
Behavioral and Brain Functions
NLRP1 inflammasome involves in learning and memory impairments and neuronal damages during aging process in mice
Experiments in miceNLRP3 inflammasome
Thursday, September 16
Molecular Medicine Reports
Ginsenoside Rg1 ameliorates aging‑induced liver fibrosis by inhibiting the NOX4/NLRP3 inflammasome in SAMP8 mice
Experiments in miceLiver fibrosis
Monday, March 8
The Journals of Gerontology, Series A
Experimental Periodontal Disease Triggers Coronary Endothelial Dysfunction in Middle-Aged Rats: Preventive Effect of a Prebiotic β-Glucan
Experiments in animalsInterventions
Friday, August 21
Journal of the American Heart Association
Vascular Endothelial Function in Midlife/Older Adults Classified According to 2017 American College of Cardiology/American Heart Association Blood Pressure Guidelines
Study in peopleMechanisms
Sunday, June 7
Communications Biology
Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice
Experiments in animalsMechanisms
Friday, March 27
Sunday, February 2
Scientific Reports
Nox2 dependent redox-regulation of microglial response to amyloid-β stimulation and microgliosis in aging
Experiments in animalsMechanisms
Saturday, January 18
Sunday, October 6
Chemico-biological Interactions
Dipeptidyl peptidase-4 inhibition prevents vascular aging in mice under chronic stress: Modulation of oxidative stress and inflammation
Experiments in animalsInterventions
Friday, April 27
Bioscience Reports
oxLDL-mediated cellular senescence is associated with increased NADPH oxidase p47phox recruitment to caveolae
Experiments in cellsMechanisms
Monday, September 18
Nutrition Research and Practice
Luteolin and fisetin suppress oxidative stress by modulating sirtuins and forkhead box O3a expression under in vitro diabetic conditions
Experiments in human cellsFisetin
Sunday, August 20
Monday, April 17
Experimental Gerontology
Replicative senescence promotes prothrombotic responses in endothelial cells: Role of NADPH oxidase- and cyclooxygenase-derived oxidative stress
Experiments in pig cellsOxidative stress and ROS signaling
Friday, August 19
Experimental Gerontology
Age-related alterations in the sarcolemmal environment are attenuated by lifelong caloric restriction and voluntary exercise
Experiments in ratsDietary restriction
Tuesday, August 2
Experimental Gerontology
TNFA gene variants related to the inflammatory status and its association with cellular aging: From the CORDIOPREV study
Genetic association study of 840 peopleInflammation
Tuesday, July 19
Hypertension
Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic Stiffness
Experiments in miceArterial stiffness
Thursday, November 5
The Journal of Biological Chemistry
Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice
Experiments in miceMechanisms