P21 Cip1

1 paper

Animals1

Latest

3 in 12 months

Brain Communications28 Aug

NOR1 loss relates to inflammation and biological ageing in multiple sclerosis motor cortex

Cohort study of 50 peopleInflammation

Gene5 Feb

Mammalian senescent nurse cell provides Trichinella spp. muscle larvae with cell growth inhibitory capacity

Experiments in miceCellular senescence

Journal of the American Society of Nephrology21 Jan

The Aging Kidney and Acute Kidney Injury

ReviewKidney

Frontiers in Aging30 Oct

Sirolimus use in allogeneic hematopoietic cell transplant recipients: assessing its senotherapeutic role in a high risk population

Cohort study in peopleRapamycin

bioRxiv5 Sep

Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers

Preprint: experiments in miceSenolytics

bioRxiv14 Jul

A human and mouse subpopulation of senescent β-cells induces pathologic dysfunction through targetable paracrine signaling

Preprint: study in peopleInterventions

Science Signaling24 Nov

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells

Experiments in miceBlood and immune system

Molecular Cell21 May

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

Experiments in human cellsTelomerase and telomere maintenance