Papers on NOX4 expression

23 papers

Saturday, September 26

Biochemical PharmacologySep 26

Trans-zeatin suppresses osteoclastogenesis and prevents estrogen deficiency-induced bone loss by modulating Nrf2-mediated redox homeostasis and AKT signaling

Experiments in miceBones and joints

Paper

Friday, June 19

Frontiers in ImmunologyJun 19

Senescence-circadian interplay stratifies patient prognosis and reveals immune remodeling heterogeneity in colorectal cancer

Cohort study of 120 peopleColorectal cancer

Paper

Friday, June 12

ACS Applied Materials & InterfacesJun 12

ROS-Responsive H₂S Release Attenuates Renal Aging by Preserving Mitochondrial Function and Mitigating Oxidative Stress

Experiments in miceKidney

Paper

Friday, May 29

International ImmunopharmacologyMay 29

Nox4 mediates chondrocyte senescence and cartilage degradation in post-traumatic osteoarthritis via the ROS/p38MAPK signaling pathway

Experiments in micep38 MAPK signaling

Paper

Monday, February 9

Clinical ScienceFeb 9

Intrarenal renin-angiotensin system inactivation ameliorates tubulopathy via attenuation of mitochondrial oxidative stress, dysfunction and senescence in diabetes

Experiments in miceRenin–angiotensin system

Paper

Friday, January 16

Stem Cell Research & TherapyJan 16

Klotho protects the osteogenic function of human periodontal ligament stem cells in periodontitis by inhibiting NOX4-mediated ferroptosis

Experiments in micePeriodontitis

Paper

Monday, July 21

Physiological ResearchJul 21

Trigonelline attenuated sepsis-induced acute kidney injury by activating NAD+/SIRT1 Pathway

Experiments in miceAcute kidney injury

Paper

Thursday, September 5

Aging CellSep 5

Targeting TGF-β signaling, oxidative stress, and cellular senescence rescues osteoporosis in gerodermia osteodysplastica

Experiments in miceOsteoporosis

Paper

Saturday, July 13

International Journal of Molecular SciencesJul 13

miR-146a Decreases Inflammation and ROS Production in Aged Dermal Fibroblasts

Experiments in mouse cellsOxidative stress and ROS signaling

Paper

Sunday, December 24

Behavioural Brain ResearchDec 24

Empagliflozin alleviates diabetes-induced cognitive impairments by lowering nicotinamide adenine dinucleotide phosphate oxidase-4 expression and potentiating the antioxidant defense system in brain tissue of diabetic rats

Experiments in 8 ratsEmpagliflozin

Paper

Friday, June 2

Cell TransplantationJun 2

Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis

Experiments in miceCellular senescence

Paper

Thursday, December 1

Redox ReportDec 1

Fisetin ameliorates oxidative glutamate testicular toxicity in rats via central and peripheral mechanisms involving SIRT1 activation

Experiments in 40 ratsFisetin

Paper

Tuesday, August 9

PeerJAug 9

Advanced oxidation protein products induce annulus fibrosus cell senescence through a NOX4-dependent, MAPK-mediated pathway and accelerate intervertebral disc degeneration

Experiments in ratsMAPK/ERK signaling

Paper

Saturday, April 9

Redox BiologyApr 9

Mechano-signaling via Piezo1 prevents activation and p53-mediated senescence of muscle stem cells

Experiments in miceCellular senescence

Paper

Sunday, October 4

Redox BiologyOct 4

The correlation of IRE1α oxidation with Nox4 activation in aging-associated vascular dysfunction

Experiments in miceMechanisms

Paper

Thursday, September 24

HepatologySep 24

The Apelin-Apelin Receptor Axis Triggers Cholangiocyte Proliferation and Liver Fibrosis During Mouse Models of Cholestasis

Experiments in miceMechanisms

Paper

Tuesday, August 18

JBMR PlusAug 18

Nox4 Expression Is Not Required for OVX-Induced Osteoblast Senescence and Bone Loss in Mice

Experiments in miceCellular senescence

Paper

Sunday, February 23

BiomoleculesFeb 23

Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology

ReviewMechanisms

Paper

Saturday, August 17

Redox BiologyAug 17

Increased mitochondrial NADPH oxidase 4 (NOX4) expression in aging is a causative factor in aortic stiffening

Experiments in miceMitochondrion

Paper

Sunday, January 8

American Journal of Physiology Lung Cellular and Molecular PhysiologyJan 8

Dysregulated Nox4 ubiquitination contributes to redox imbalance and age-related severity of acute lung injury

Experiments in miceLung

Paper

Sunday, December 18

Journal of Molecular and Cellular CardiologyDec 18

NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis

Study in peopleInflammation

Paper

Friday, September 23

OncotargetSep 23

NOX4 downregulation leads to senescence of human vascular smooth muscle cells

Experiments in human cellsCellular senescence

Paper

Tuesday, August 16

Life SciencesAug 16

NADPH oxidase-4 and MATER expressions in granulosa cells: Relationships with ovarian aging

Cross-sectional study in peopleReproductive system

Paper