NMNAT2

There is 1 paper on NMNAT2 in aging research: none in people yet, 1 in cells.

1 paper studies it25 more mention it

Cells1

Latest

3 papers in 12 months

Scientific ReportsApr 14

SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways

Experiments in mouse cellsInterventions

Frontiers in AgingSep 3

A minimal three-arm oral regimen for healthspan: mechanistic alignment with transcriptomic signals from a large parental-lifespan GWAS

CommentaryInterventions

CNS Neuroscience & TherapeuticsJul 29

hUC-MSCs via β-NGF Alleviate Cognitive Impairment After Tibial Fracture Surgery by Regulating the STMN2/NMNAT2-SARM1-NF-κB Signaling Pathway

Experiments in miceBones and joints

FigshareApr 7

Tissue-Resolved Transcriptome-Wide Association Study Reveals Targeted NAD⁺ Salvage, Synaptic Refinement, and Reduced Insulin Drive as Transcriptional Mechanisms of Human Lifespan

Preprint: computational studySynapse

FASEB JournalFeb 18

Nmnat2 deficiency in the arcuate nucleus or paraventricular nucleus induces Sarm1-independent neuron loss and liraglutide-reversible obesity

Experiments in miceLiraglutide

Cell Death & DiseaseJan 17

Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD⁺ metabolism

Experiments in human cellsNAD+ metabolism

Molecular NeurobiologyOct 1

Chronically Low NMNAT2 Expression Causes Sub-lethal SARM1 Activation and Altered Response to Nicotinamide Riboside in Axons

Experiments in miceMechanisms

PLOS OneApr 16

Activated NAD+ biosynthesis pathway induces olaparib resistance in BRCA1 knockout pancreatic cancer cells

Experiments in human cellsNAD+ metabolism

Food & FunctionMar 18

β-Nicotinamide mononucleotide supplementation prolongs the lifespan of prematurely aged mice and protects colon function in ageing mice

Experiments in miceNicotinamide mononucleotide

Molecular NeurodegenerationJan 28

NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport

Experiments in miceGlycolysis