Neuronal DNA damage

There are 2 papers on neuronal DNA damage in aging research: none in people yet, 1 in animals, 1 in cells.

2 papers study it4 more mention it1 finding

See all 6 papers on neuronal DNA damage

Animals1
Cells1

Upstream

1

STING1

downin mice1

1 study

STING1 protects against neuronal DNA damage in mice (shown by STING deficiency (knockout) in physiologically aged mice).
“STING deficiency leads to an accrual of neuronal DNA damage”
Animalsshown by STING deficiency (knockout) in physiologically aged miceneurons
Microglial STING is a central safeguard against neurological decline with age
Cell reportsMay 31, 2025

Latest

Cell ReportsJun 2

Microglial STING is a central safeguard against neurological decline with age

Experiments in miceSTING1

Brain PlasticityDec 20

Nicotinamide Mononucleotide Prevents Cisplatin-Induced Mitochondrial Defects in Cortical Neurons Derived from Human Induced Pluripotent Stem Cells

Experiments in human cellsNicotinamide mononucleotide

Disease Models & MechanismsJul 31

Evidence of neuronal DNA damage in the brains of patients with Rett syndrome

Cross-sectional study in peopleDNA damage response

NeuronJan 10

DNA damage and its links to neuronal aging and degeneration

ReviewMechanisms

GliaAug 12

Metallothionein-I/II expression associates with the astrocyte DNA damage response and not Alzheimer-type pathology in the aging brain

Study in peopleMechanisms

Nutritional NeuroscienceJun 2

Increased total DNA damage and oxidative stress in brain are associated with decreased longevity in high sucrose diet fed WNIN/Gr-Ob obese rats

Experiments in ratsDNA damage response