Journal of Neuroinflammation
Air pollution changed brain immune cell activity in mice
A 20-week mouse experiment found that genetic background shaped how brain immune cells responded to fine-particle air pollution.A 20-week mouse experiment found that genetic background shaped how brain immune cells responded to fine-particle air pollution.
Mouse studyMechanisms
Who was studied5xFAD mice and wild-type littermates, 20 weeks, against mice breathing filtered air
What changedPollution changed brain immune cells’ gene activity and DNA accessibility compared with filtered air, with responses depending on genetic background
The catchMice inhaled concentrated pollution rather than ordinary ambient air