mTOR gene expression

1 paper1 finding

Human trial1

Interventions

1

Metformin

upin humans1

1 study

Metformin increases mTOR gene expression in humans.
“elevated mTOR gene expression with concomitant reduction in p70S6K phosphorylation in subjects' PBMCs”
Human trialprediabetes; comparison with baselineperipheral blood mononuclear cells1500 mg/day2 monthsn = 38
Metformin improves putative longevity effectors in peripheral mononuclear cells from subjects with prediabetes. A randomized controlled trial
Nutrition, metabolism, and cardiovascular diseases : NMCD24 Mar 2015

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