1 paper
National Institute of Neurological Disorders and StrokeUS$1.4mNational Institute for Occupational Safety and HealthUS$498.7kVeterans Affairs
Clonal hematopoiesis in monocytes contributes to HIV-associated neuroinflammation
National Institute of Neurological Disorders and StrokeGeorge Washington UniversityUS$472.6k2022–2027
National Institute for Occupational Safety and HealthState University New York Stony BrookUS$498.7k2021–2024
Mice lacking the receptor FXR showed poorer immune cell recruitment and delayed liver regrowth after surgical removal of most of the organ.Mice lacking the receptor FXR showed poorer immune cell recruitment and delayed liver regrowth after surgical removal of most of the organ.
In cellular models, dysferlin promoted inflammatory macrophage responses, and dysferlin-enriched macrophages suppressed muscle cell differentiation and fusion in…In cellular models, dysferlin promoted inflammatory macrophage responses, and dysferlin-enriched macrophages suppressed muscle cell differentiation and fusion in co-culture.
One lung immune cell population increased more than 10-fold in old mice compared with younger mice.One lung immune cell population increased more than 10-fold in old mice compared with younger mice.
The endoPRS-SS framework boosted computational efficiency up to 90-fold while using summary statistics and multiple endophenotypes to improve Alzheimer's disease risk…The endoPRS-SS framework boosted computational efficiency up to 90-fold while using summary statistics and multiple endophenotypes to improve Alzheimer's disease risk prediction.
Researchers identified a transient senescent-like monocyte state governed by the transcription factor AP-1 that primes cells toward inflammatory and sepsis-associated…Researchers identified a transient senescent-like monocyte state governed by the transcription factor AP-1 that primes cells toward inflammatory and sepsis-associated states.
In a randomized trial of 40 older adults with chronic traumatic brain injury, fenofibrate lowered plasma neurofilament light chain levels and improved cognitive function.In a randomized trial of 40 older adults with chronic traumatic brain injury, fenofibrate lowered plasma neurofilament light chain levels and improved cognitive function.