B cell levels
4 papers1 finding
- Human trial2
- Humans1
- Animals1
Upstream
1USP26
downin mice1
1 study
USP26
downin mice1
USP26 decreases B cell levels in mice.
“mice with USP26 deficiency in osteoblasts died earlier in sepsis conditions with decreased B cells”
Animalsosteoblast-specific conditional knockout
Osteoblastic USP26 regulates B lymphopoiesis by endogenous tryptophan metabolites
Journal of advanced research11 Feb 2026
Funding
25 grants since 2022National Institute of Allergy and Infectious DiseasesUS$19mNational Institute on AgingUS$6.5mNational Institute of Neurological Disorders and StrokeUS$882.9k
TFEB and age-associated B cells in autoimmunity
National Institute of Arthritis and Musculoskeletal and Skin DiseasesMayo Clinic RochesterUS$377.3k2025–2027
Obesity-driven alterations in humoral B cell immunity
National Institute of Allergy and Infectious DiseasesUniversity of Texas Hlth Science CenterUS$2.2m2025–2029
National Institute of Allergy and Infectious DiseasesColumbia Univ New York MorningsideUS$512.2k2023–2027
Sex Specific Regulation of B1 B Cell Self-Renewal and Natural Antibody Production
National Institute of Allergy and Infectious DiseasesWestern Michigan Univ School of MedicineUS$78k2023–2026
National Institute of Allergy and Infectious DiseasesUniversity of PennsylvaniaUS$37.1k2023–2026
Prevalence, etiology, and clinical implications of low count monoclonal B-cell lymphocytosis (MBL)
National Institute on AgingMayo Clinic RochesterUS$3.4m2018–2029
B Cells Directly Alter Adaptive Plasticity to Support Functional Recovery After Stroke
National Institute of Neurological Disorders and StrokeUniversity of KentuckyUS$389.7k2015–2027
How Distinct Age-Associated B Cell Subsets Can Protect the Aged from Influenza
National Institute of Allergy and Infectious DiseasesUniv of Massachusetts Med Sch WorcesterUS$586.1k2024–2029
Age-associated changes in B cell and antibody effector responses to Streptococcus pneumoniae
National Institute of Allergy and Infectious DiseasesWake Forest University Health SciencesUS$49.5k2025–2028
Hydrogel-Based Aged Immune Organoids to Study Epigenetics and Trajectory of B Cells
National Institute of Allergy and Infectious DiseasesGeorgia Institute of TechnologyUS$741k2024–2029