Lymphocytes

Biomarker1 paper

  • Humans1

Funding

National Institute of Allergy and Infectious DiseasesUS$2.8mNational Heart, Lung, and Blood InstituteUS$169kNational Institute of Diabetes and Digestive and Kidney DiseasesUS$163.6k4 grants since 2013

Latest

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iScienceCells

Retinal barrier B cells vary with age and antibody availability

Experiments in isolated retinal barrier B cells linked aging and the availability of immunoglobulin M, a type of antibody, to how active the cells…Experiments in isolated retinal barrier B cells linked aging and the availability of immunoglobulin M, a type of antibody, to how active the cells were.

European Journal of PharmacologyAnimals

Tetanus vaccine ingredient improved learning and memory in aging mice

An experiment in twelve-month-old mice found better learning and memory alongside more immature nerve cells and greater insulation around nerve…An experiment in twelve-month-old mice found better learning and memory alongside more immature nerve cells and greater insulation around nerve fibres.

Frontiers in ImmunologyAnimals

Fungus drives spleen aging in mice, eased by astragaloside IV

In aged mice, Kazachstania pintolopesii aggravated spleen damage and immune cell ferroptosis, while astragaloside IV treatment restored immune…In aged mice, Kazachstania pintolopesii aggravated spleen damage and immune cell ferroptosis, while astragaloside IV treatment restored immune function and iron homeostasis.

Molecular Genetics and GenomicsHumans

Higher CALLY index is causally linked to lower dementia risk

Mendelian randomization across more than 265,000 UK Biobank and FinnGen participants linked a higher CALLY score to reduced dementia risk but…Mendelian randomization across more than 265,000 UK Biobank and FinnGen participants linked a higher CALLY score to reduced dementia risk but increased sleep disorder risk.