Mitochondrial protein synthesis
5 papers study it12 more mention it3 findings
- Animals5
Interventions
3Metformin + rapamycin
downin mice1
1 study
Metformin + rapamycin
downin mice1
Metformin + rapamycin decreases mitochondrial protein synthesis in mice.
“RAP+MET decreased mitochondrial protein synthesis in young females.”
Animalsin whole brainbrain8 weeksfemales
The journals of gerontology. Series A, Biological sciences and medical sciences
Rapamycin
no changein mice1
1 study
Rapamycin
no changein mice1
Rapamycin has no effect on mitochondrial protein synthesis in mice.
“In both sexes, mito protein synthesis was maintained in skeletal muscle from Rap”
Animalsskeletal muscle12 weeks
The journals of gerontology. Series A, Biological sciences and medical sciences
Caloric restriction
downin mice1
1 study
Caloric restriction
downin mice1
Caloric restriction decreases mitochondrial protein synthesis in mice.
“liver mitochondrial protein synthesis was lower in CR mice versus AL mice”
Animalsliver
Calorie restriction does not increase short-term or long-term protein synthesis
The journals of gerontology. Series A, Biological sciences and medical sciences
Latest
Frontiers in Cell and Developmental Biology
Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction
ReviewMechanisms
Frontiers in Physiology
The Dunkin Hartley Guinea Pig Is a Model of Primary Osteoarthritis That Also Exhibits Early Onset Myofiber Remodeling That Resembles Human Musculoskeletal Aging
Experiments in animalsMechanisms
Aging Cell
Proteomic signatures of in vivo muscle oxidative capacity in healthy adults
Study in peopleMechanisms
The Journals of Gerontology, Series A
Brain Protein Synthesis Rates in the UM-HET3 Mouse Following Treatment With Rapamycin or Rapamycin With Metformin
Experiments in miceRapamycin
Frontiers in Physiology
Metabolic Reprogramming Promotes Myogenesis During Aging
Experiments in animalsInterventions
The Journals of Gerontology, Series A
Differential Effects of Rapamycin and Metformin in Combination With Rapamycin on Mechanisms of Proteostasis in Cultured Skeletal Myotubes
Experiments in cellsInterventions