1 paper
National Institute on AgingUS$818.3kNational Institute of Arthritis and Musculoskeletal and Skin DiseasesUS$174.4k
Boosting protein synthesis using antisense oligonucleotides to treat neurodegeneration
National Institute on AgingWashington UniversityUS$53.9k2024–2026
National Institute on AgingWake Forest University Health SciencesUS$352k2021–2026
Role of FK506-Binding Protein 3 (FKBP3) as a Novel Regulator of Skeletal Muscle Protein Synthesis
National Institute of Arthritis and Musculoskeletal and Skin DiseasesIndiana University IndianapolisUS$174.4k2022–2024
In aged roundworms, a low dose of zinc restored organismal zinc after an approximately 90% drop in zinc-to-sulfur ratio, improving healthspan and stress resistance.In aged roundworms, a low dose of zinc restored organismal zinc after an approximately 90% drop in zinc-to-sulfur ratio, improving healthspan and stress resistance.
In a PolgA-mutant mouse model, gut microbiota reduced systemic mitochondrial function while driving energy-demanding immune remodeling and protein synthesis through mTOR…In a PolgA-mutant mouse model, gut microbiota reduced systemic mitochondrial function while driving energy-demanding immune remodeling and protein synthesis through mTOR signaling.
A genetic screen and functional assays show that falling translational capacity causes meiotic and developmental defects during oocyte aging.A genetic screen and functional assays show that falling translational capacity causes meiotic and developmental defects during oocyte aging.