Mitochondrial NAD+

7 papers study it40 more mention it1 finding

Animals4
Cells3

Interventions

1

Nicotinamide mononucleotide

upin mice1

1 study

Nicotinamide mononucleotide increases mitochondrial NAD+ in mice.
“NMN, administered to male mice, increases hippocampal mitochondria NAD+ pools for up to 24 hr posttreatment”
Animalshippocampus62.5 mg/kgUp to 24 hr posttreatmentmales
Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3-dependent mechanism in male mice
Journal of neuroscience researchFeb 23, 2019

More on Nicotinamide mononucleotide

Funding

1 grant since 2022

National Heart, Lung, and Blood InstituteUS$34.3k

Loss of mitochondrial NAD+ as a unifying cause of heart failure
National Heart, Lung, and Blood InstituteUniversity of PennsylvaniaUS$34.3k2022–2025

Latest

11 papers in 12 months

Preprints.orgOct 17

NAD⁺/NADH as the Electrochemical Currency and Other Specific Electron Transfer Molecules in Health and Disease

Preprint: reviewMechanisms

Ageing Research ReviewsAug 17

NAD⁺ circuits in aging, tissue repair and fibrosis

ReviewMechanisms

FigshareApr 28

Toward Precision Psychiatry in Major Depressive Disorder: A Symptom-Level Bioenergetic-Plasticity Model Linking Mitochondrial Function, NAD⁺ Metabolism, and Treatment Response

Preprint: reviewNAD+ metabolism

Aging CellApr 22

The Mitochondrial NAD Transporter SLC25A51 in Adipocytes Regulates Adipose Tissue Mitochondrial Function and Systemic Metabolism During Aging

Experiments in miceNAD+ metabolism

FigshareApr 1

Augmented Cheung Glutamatergic Regimen as a Candidate for Investigation in Amyotrophic Lateral Sclerosis

Preprint: commentaryAmyotrophic lateral sclerosis

Journal of Molecular Cell BiologyMar 30

NAD+ subcellular partitioning mediated by miR-183 and miR-96 regulates muscle stem cell differentiation

Experiments in animalsStem cell differentiation

FigshareMar 30

Polygenic Constraints on NAD⁺ Metabolism in Major Psychiatric Illness: Mechanistic Support for NMN Supplementation

Preprint: computational studyNAD+ metabolism

Frontiers in Aging NeuroscienceFeb 20

Changes in the brain [NAD⁺]/[NADH] and [NADPH]/[NADP⁺] with aging and anti-aging dietary restriction

Computational studyMechanisms

ZenodoJan 2

The NuRD Sink and Photonic Rewiring: A Systems-Level Hypothesis of Epigenetic Recovery

Preprint: commentaryMechanisms

Aging and DiseaseJan 1

Extension of Lifespan and Amelioration of Alzheimer's Disease Phenotypes by Genetic Manipulation of Mitochondrial NAD⁺/NADH Ratio

Experiments in fliesMitochondrion