Stem Cell Reports
Bile acid from gut microbes disrupts blood stem cells in mice
In mouse experiments, prolonged exposure to a gut microbial bile acid contributed to blood stem cell loss, while a high-fiber diet reduced age-associated decline.In mouse experiments, prolonged exposure to a gut microbial bile acid contributed to blood stem cell loss, while a high-fiber diet reduced age-associated decline.
Mouse studyInterventions
Who was studiedMice
What changedProlonged DCA administration contributed to blood-forming stem cell loss in mice
The catchAdministered DCA exposure could differ from the natural increases seen during aging