Mevalonate

1 paper

Animals1

Latest

8 in 12 months

International Journal of Molecular SciencesYesterday

A Mechanistic Framework for Somatic Mosaicism in Autoinflammatory Diseases Beyond Mendelian Inheritance

ReviewMechanisms

Journal of Lipid and Atherosclerosis1 Oct

Statin Use and Site-Specific Cancer Risk: A Nationwide Cohort Study Using Korean Health Insurance Data

Cohort study of 232,133 peopleCancer

Journal of Cachexia, Sarcopenia and Muscle23 Sep

Exploring the Impact of Urolithins A and B on Muscle Health: A Transcriptomic Analysis in Human Myotubes

Experiments in human cellsMuscle

Frontiers in Pharmacology29 Aug

Protein farnesylation: from molecular mechanisms to therapeutic targeting in cancer, aging, and beyond

ReviewMechanisms

Frontiers in Pharmacology7 Aug

Beyond cardiovascular protection: a conceptual and translational review of the hepato-specific mechanisms of statins in metabolic dysfunction-associated steatotic liver disease (MASLD)

Zenodo28 Apr

Autophagy Enhancement with Spermidine and Rapamycin Microdosing

Preprint: commentaryInterventions

Hepatology3 Feb

Age and sex influence transcriptomic responses to statin therapy that control liver aging during systemic metabolic dysfunction

Cohort study of 368 peopleStatins

Aging Cell12 Jan

Decreased PTGES2 Farnesylation in Granulosa Cells Compromises PGE2-Dependent Cumulus Expansion and Oocyte Maturation During Ovarian Aging

Experiments in miceReproductive system

Nature Aging27 Aug

Mevalonate metabolites boost aged oocyte quality through prenylation of small GTPases

Experiments in miceInterventions

Life Sciences17 Aug

Exercise improves aging-induced cardiac dysfunction and prolongs lifespan via Hmgcr

Experiments in fliesExercise