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Methylation levels

There is 1 paper on methylation levels in aging research: none in people yet, 1 in animals. The newest story, Oct 26, 2026: “Endometriosis and linked ovarian cancer show opposite biological aging”.

Biomarker

1 paper studies it441 more mention it2 findings

12 new papers in 30 daysSee all 442

  • Animals1

Associations

2

Chronological age

mixedin silico1

1 study

  1. Methylation levels are associated with chronological age in silico (nonlinear (power law) in more than 15% of cases).

    “the methylation level itself in more than 15% cases varies nonlinearly with age (according to the power law)”

    In silico

    Disentangling age-dependent DNA methylation: deterministic, stochastic, and nonlinear

    Scientific reports

Methylation variability

upin silico1

1 study

  1. Methylation levels are associated with methylation variability in silico (quadratic dependence in about 90% of age-associated differentially methylated positions).

    “in about 90% of the age-associated differentially methylated positions, the variability changes as the square of the methylation level”

    In silico

    Disentangling age-dependent DNA methylation: deterministic, stochastic, and nonlinear

    Scientific reports

More on Methylation variability

Funding

60 grants since 2018

National Institute on Aging$23.1MNational Cancer Institute$9.7MNational Institute on Minority Health and Health Disparities$9.1M

Latest

Nov 2025: 4Dec 2025: 6Jan 2026: 4Feb 2026: 4Mar 2026: 6Apr 2026: 7May 2026: 3Jun 2026: 10Jul 2026: 3Aug 2026: 5Sep 2026: 6Oct 2026: 765 papers in 12 months
BMC Medicine

Endometriosis and linked ovarian cancer show opposite biological aging

Biological age was 16.92% higher than chronological age in endometriosis patients but 14.64% lower in patients with related ovarian cancer.Biological age was 16.92% higher than chronological age in endometriosis patients but 14.64% lower in patients with related ovarian cancer.

Case-control studyEndometriosis
Paper
Journal of the American Heart Association

Genetic analysis links a blood enzyme to Alzheimer’s risk

Genetic analysis linked inhibition of a blood-pressure enzyme to higher Alzheimer’s odds, with an odds ratio of 1.10.Genetic analysis linked inhibition of a blood-pressure enzyme to higher Alzheimer’s odds, with an odds ratio of 1.10.

Mendelian randomizationAlzheimer's disease
Paper
Environmental Epigenetics

DNA marks may help track sun exposure in human skin

In a five-month intervention involving 42 people, sunscreen-treated arms showed smaller changes in DNA marks than the opposite arms under everyday conditions.In a five-month intervention involving 42 people, sunscreen-treated arms showed smaller changes in DNA marks than the opposite arms under everyday conditions.

Randomized trial · 42 peopleSun exposure
Paper

See all 442

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