2 papers2 findings
Ovary transplantation
downin mice1
Ovary transplantation decreases liver transcriptomic age in mice.
“young ovaries also lowered the transcriptomic age of aged liver and brain”
Animalsyoung donor ovariesliver
Ovarian age measures partly shift towards host age in mice
bioRxiv13 Oct 2026Preprint
Liver regeneration
downin mice1
Liver regeneration is associated with liver transcriptomic age in mice.
“liver regeneration after partial hepatectomy in old animals also led to a decreased transcriptomic age”
Animalsregeneration after partial hepatectomyliver
Intestinal repair linked to lower gene-based age estimates in mice
bioRxiv13 Oct 2026Preprint
Transplanting ovaries between younger and older mice shifted molecular age estimates in both directions, but the changes remained partial.Transplanting ovaries between younger and older mice shifted molecular age estimates in both directions, but the changes remained partial.
In injury experiments, intestinal cells temporarily had lower gene-based age estimates, with the timing differing between young and old mice.In injury experiments, intestinal cells temporarily had lower gene-based age estimates, with the timing differing between young and old mice.