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Liver fibrosis

There are 4 papers on liver fibrosis in aging research: 2 trials in people, 2 in animals. The newest story, Oct 30, 2026: “Blood protein links to dementia vary with liver scarring score”.

Biomarker

4 papers study it453 more mention it1 finding

29 new papers in 30 daysSee all 457

  • Human trial2
  • Animals2

Interventions

1

Weight reduction

no changein humans1

1 study

  1. Weight reduction showed no clear effect on liver fibrosis in humans (any amount of weight reduction in lean and non-lean NASH).

    “In both lean and non-lean groups, weight reduction of any amount was associated with significant reduction of steatosis, ballooning and NAS, except lobular inflammation and fibrosis.”

    Human trialany amount of weight reduction in lean and non-lean NASHliver1 year

    Effect of Weight Reduction on Histological Activity and Fibrosis of Lean Nonalcoholic Steatohepatitis Patient

    Journal of translational internal medicine

More on Weight reduction

Funding

6 grants since 2018

National Institute on Drug Abuse$2.8MNatural Science Foundation of Hunan ProvinceJapan Society for the Promotion of Science¥4.3M

Latest

Dec 2025: 7Jan 2026: 6Feb 2026: 14Mar 2026: 16Apr 2026: 4May 2026: 1Jun 2026: 9Jul 2026: 8Aug 2026: 17Sep 2026: 13Oct 2026: 23Nov 2026: 0118 papers in 12 months
Journal of Alzheimer's Disease Reports

Blood protein links to dementia vary with liver scarring score

In 48,754 dementia-free UK Biobank participants, nine blood proteins had links to later dementia that differed with a liver scarring index.In 48,754 dementia-free UK Biobank participants, nine blood proteins had links to later dementia that differed with a liver scarring index.

Cohort · 48,754 peopleAll-cause dementia
Paper
JACC Advances

Fatty liver helped predict heart and liver risks

An observational study of 313,970 UK Biobank participants found that fatty liver measures improved risk prediction beyond staging heart, kidney and metabolic health.An observational study of 313,970 UK Biobank participants found that fatty liver measures improved risk prediction beyond staging heart, kidney and metabolic health.

Cohort · 313,970 peopleBiomarkers
Paper
ESC Congress 2026 Abstract

Combined liver and other health risks linked to higher mortality

Adults with high liver risk and advanced heart-kidney-metabolic risk had 621% higher relative mortality risk than those with low liver risk and early-stage risk.Adults with high liver risk and advanced heart-kidney-metabolic risk had 621% higher relative mortality risk than those with low liver risk and early-stage risk.

Cohort · 28,056 peoplePopulations
Paper

See all 457

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