LivAge

1. Rapamycin decreases LivAge in silico.

   “as well as rapamycin supplementation in specific contexts), reduce the transcriptomic age estimated by the clock.”

   In silicoin specific contextsliver

   LivAge: An Online Aging Clock for Murine Transcriptomic Age Estimation

   Aging cell·22 Aug 2026

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1. Caloric restriction decreases LivAge in silico.

   “environmental (caloric, protein, or methionine restriction, as well as rapamycin supplementation in specific contexts), reduce the transcriptomic age estimated by the clock.”

   In silicoliver

   LivAge: An Online Aging Clock for Murine Transcriptomic Age Estimation

   Aging cell·22 Aug 2026

More on Caloric restriction

1. Progeria increases LivAge in silico.

   “Applying the clock to accelerated-aging models revealed an increased transcriptomic age in progeroid syndromes, demonstrating its ability to capture aging-related biological processes.”

   In silicoprogeroid syndromesliver

   LivAge: An Online Aging Clock for Murine Transcriptomic Age Estimation

   Aging cell·22 Aug 2026

More on Progeria