There are 2 papers on LINE1 in aging research: 1 observational study in people, 1 in animals.
2 papers study it29 more mention it
- Humans1
- Animals1
Latest
5 papers in 12 monthsCellular Signalling
Nuclear SIRT6 depletion activates LINE1-cGAS-STING pathway to induce PASMCs senescence in hypoxic pulmonary hypertension
Experiments in animalscGAS–STING signaling
Alzheimer's & Dementia
Human herpesvirus-associated transposable element activation in human aging brains with Alzheimer's disease
Cohort study in peopleAlzheimer's disease
Research Square
Centenarian SIRT6 variants elevate SIRT6 protein and enhance cellular senescence resistance
Preprint: experiments in human cellsCellular senescence
Nucleic Acids Research
DAXX governs the silencing of LINE1 during spermatogenesis in mice
Experiments in miceMechanisms
bioRxiv
Balance between DNA repair, LINE1 suppression and lifespan in mice with SIRT6 Serine 10 phosphorylation site mutations
Preprint: experiments in miceDNA repair
Bioinformatics and Biology Insights
Structural Insights Into centSIRT6: Bioinformatic Analysis of N308K and A313S Substitution Effects
Computational studyMechanisms