MechanismsAnimals
cGAS-deficient mice display premature aging associated with derepression of LINE1 elements and inflammation
Nature Aging
The paper
Martinez JC, Morandini F, Rechsteiner C et al.
Nature Aging · 25 Aug 2026
More on Inflammation
Transitional senescent monocytes drive age-related inflammation in humans
bioRxiv · 2 Oct 2026
SATB1 loss reshapes 3D genome in mouse naive T cells
Science Advances · 2 Oct 2026
Nucleoli buffer displaced heterochromatin to limit premature aging programs in cells
bioRxiv · 2 Oct 2026
Inhibiting CHK2 improves oocyte quality and reduces ovarian inflammation in aged mice
bioRxiv · 2 Oct 2026
