Lgr5+ stem cells

3 papers2 findings

Animals3

Interventions

1

Caloric restriction

downin mice1upin mice1

2 studies

Caloric restriction decreases Lgr5+ stem cells in mice.
“calorie restriction decreased gastric Lgr5+ stem cells”
Animalsin stomach of micestomach
Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells
The Journal of cell biology3 Jul 2024
Caloric restriction increases Lgr5+ stem cells in mice.
“CR leads to increased numbers of functional Lgr5+ stem cells that compete for niche occupancy”
Animalsintestine
Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine
Cell reports21 Jul 2020

More on Caloric restriction

Latest

4 in 12 months

FEBS Letters19 Jun

From mice to humans-divergent strategies for intestinal homeostasis and regeneration

ReviewCellular homeostasis

International Journal of Biological Sciences29 May

Plasticity-Driven Regeneration of Circumvallate Papilla After Lgr5+ Stem Cells Loss

Experiments in miceMechanisms

Zenodo17 May

ITU and Developmental Biology: A Single-Axiom View of Zygote-to-Adult Cell Expansion, Waddington Landscape, Yamanaka iPSC, Hox Colinearity, Morphogen Gradients, Turing Patterns, Organoids, Regeneration, Aging Hallmarks, and Teratology — Block B 4/?

Preprint: reviewMechanisms

Aging Cell20 Apr

Maladaptive Inflammatory Signaling in Old Mice Impairs Colonic Regeneration by Promoting a Sustained Fetal-Like Epithelial State

Experiments in miceInflammation

bioRxiv2 Sep

Alanine catabolism of Paneth cells maintains intestinal stem cell function during dietary restriction

Preprint: experiments in miceDietary restriction

The Journal of Cell Biology3 Jul

Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells

Experiments in miceDietary restriction

Nature Communications20 Dec

Adult stem cell activity in naked mole rats for long-term tissue maintenance

Experiments in naked mole-ratsStem cell maintenance

bioRxiv23 Mar

Calorie Restriction activates a gastric Notch-FOXO1 pathway to expand Ghrelin cells

Preprint: experiments in animalsInterventions

Research Square24 Feb

Fall of Parp3 restrains Lgr5+ stem cells proliferation and mucosal renovation in intestinal aging

Preprint: experiments in miceGut and microbiome

Cell Reports21 Jul

Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine

Experiments in miceDietary restriction