LGR5

Gene5 papers1 findingHGNC 4504NCBI Gene 8549Taxon 9606

Humans1
Animals3
Cells1

Effects

1

LGR5-positive structures per ganglionic area

downin humans1

1 study

LGR5 decreases LGR5-positive structures per ganglionic area in humans (0.63 ± 0.07 ×10−3 vs. 0.26 ± 0.03 ×10−3).
Humansageingascending colon myenteric ganglia
Reduced number of epithelial tuft cells and density of LGR5 expression in the myenteric plexus of the ageing human colon · Acta histochemica · 2 Sep 2026

LGR5-positive structures per ganglionic area →

Latest

5

bioRxivCellsPreprint24 Sep

LGR5 and SOX2 expressing progenitor cells in the adult and aged human and mouse inner ear have the potential to produce Myosin 7A positive cells in vitro

British Journal of PharmacologyAnimals17 Sep

Alamandine/MrgD pathway modulates gut-bone marrow axis in ageing

Gut and microbiome

Acta HistochemicaHumans3 Sep

Reduced number of epithelial tuft cells and density of LGR5 expression in the myenteric plexus of the ageing human colon

Gut and microbiome

Chemico-biological InteractionsAnimals28 Aug

SIRT6/RXRα/retinoic acid-related signaling contributes to intestinal stem cell homeostasis during aging and is modulated by Atractylenolide II

Gut and microbiome

Biochemistry and Biophysics ReportsAnimals26 Aug

NAD⁺ metabolism influences TGF-β-associated transcriptional programs and the gut microbiota in murine models of colitis

Gut and microbiome