Lesion size

Biomarker

1 paper1 finding

Animals1

Interventions

Navitoclax

no changein mice1

1 study

Navitoclax has no effect on lesion size in mice.
“ABT-263 treatment did not change lesion size or lumen area of the brachiocephalic artery (BCA).”
Animalsin western diet-fed Apoe-/- mice with advanced atherosclerosisbrachiocephalic artery100 mg/kg/bw or 50 mg/kg/bw6 weeks or 9 weeks
Treatment of advanced atherosclerotic mice with ABT-263 reduced indices of plaque stability and increased mortality
JCI insight23 Jan 2024

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