LC activity

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Female sex

upin humans1

1 study
  1. Female sex is associated with LC activity in humans.

    “females exhibited greater LC activity in response to emotional stimuli in the context of elevated p-tau 217 and GFAP levels compared to males.”

    Humansemotional stimuli with elevated p-tau 217 and GFAP; females compared with maleslocus coeruleus

    Gene variant linked to lower brain scan signals in women

    Alzheimer's research & therapy6 Oct 2026

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Alzheimer's Research & Therapy

Gene variant linked to lower brain scan signals in women

An observational study of 101 adults aged 30–85 without cognitive impairment found no overall sex differences in a small brain region’s signals or activity.An observational study of 101 adults aged 30–85 without cognitive impairment found no overall sex differences in a small brain region’s signals or activity.

Cross-sectional study of 101 peopleMechanisms