Intercellular spacing thickness
Biomarker1 paper1 finding
- Human trial1
Interventions
1XEPTM-716 miniproteintm
downin humans1Low certainty
1 study
XEPTM-716 miniproteintm
downin humans1Low certainty
XEPTM-716 miniproteintm decreases intercellular spacing thickness in humans (p = 0.030).
Human trialsplit-face vs vehicletopicalstratum granulosum2.5%56 daysfemalesn = 25
AI-Assisted Quantitative Reflectance Confocal Microscopy Reveals Modulation of Senescence-Associated Epidermal Morphometric Features by a Topical TGF-β Mimetic, XEP™-716 Miniprotein™ · Dermatology and therapy · 1 Oct 2026