Inflammation- and senescence-associated proteins

1. Caloric restriction decreases inflammation- and senescence-associated proteins in humans.

   “Following the intervention, multiple proteins associated with inflammation and senescence were significantly reduced, reversing the increase commonly associated with aging.”

   Human trialprediabetes; participants who achieved at least 12% weight lossseverely energy-restricted dietplasma8 weeksn = 44

   Short-Term Severe Energy Restriction Promotes Molecular Health and Reverses Aging Signatures in Adults With Prediabetes in the PREVIEW Study

   Aging cell·16 Jun 2025

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