Immunosenescent cells

1 paper1 finding

Animals1

Interventions

1

AAV-LAV-BPIFB4

downin mice1

1 study

AAV-LAV-BPIFB4 decreases immunosenescent cells in mice.
“Notably, AAV-LAV-BPIFB4 gene transfer in aged mice reduced the pool of peripheral immunosenescent cells”
Animalsaged mice
Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38⁺ macrophages and NAD⁺ decline
Cell death & disease27 Jan 2022

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Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38⁺ macrophages and NAD⁺ decline

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