Immune cell composition

Biomarker

2 papers1 finding

  • Human trial1
  • Humans1

Associations

1

Principal component-based DNAm clocks

upin humans1

1 study
  1. Immune cell composition is associated with principal component-based DNAm clocks in humans.

    “A total of 24 of the 43 immune cell phenotypes and 55 of the 68 inflammatory proteins investigated were significantly associated with at least one of six DNAm aging metrics”

    Humansaverage of 6 years later

    Immune cells and inflammatory proteins are differentially associated with subsequent DNA methylation biological aging measures in the Framingham Heart Study Offspring Cohort

    GeroScience2 Oct 2025

More on Principal component-based DNAm clocks

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Genes

Blood methylation clocks capture two distinct biological domains of aging

Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors, and lifestyle…Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors, and lifestyle exposures.

Cohort study in peopleBiomarkers