Hyperphosphorylated tau

3 papers

Animals3

Latest

10 in 12 months

Molecular Brain8 Oct

Forced treadmill running and ladder climbing physical activity attenuates cognitive decline and protein aggregates in aged 3xTg-AD mice

Experiments in miceInterventions

bioRxiv2 Oct

Progressive behavioral and cognitive decline in Drosophila harboring AD- associated APOE4 variants

Preprint: experiments in fliesAPOE

Alzheimer's & Dementia5 Aug

Astrocyte reactivity modifies the effects of locus coeruleus norepinephrine-related dysfunction on tau and its impact on cognition

Cohort study of 78 peopleMechanisms

AAIC 2025 Abstract9 Jan

Lower resting‐state phasic locus coeruleus activity is associated with cortical tau accumulation and cognitive decline in preclinical Alzheimer's disease

Study in peopleMechanisms

AAIC 2025 Abstract7 Jan

VeraBIND Tau test, a novel plasma assay for active tau pathology, identifies individuals with positive tau‐PET signal, regardless of amyloid status

Study in peopleBiomarkers

AAIC 2025 Abstract26 Dec

Blood biomarkers of neuronal injury and glial cell dysfunction and 25‐year cognitive decline and incident dementia in the ARIC study

Study in peopleBiomarkers

AAIC 2025 Abstract25 Dec

Insulin Resistance in Human Hippocampal Pyramidal Neurons Correlates with Age in Cognitively Normal and Alzheimer's Disease Patients

Study in peopleMechanisms

AAIC 2025 Abstract23 Dec

Lower resting‐state phasic locus coeruleus activity is associated with cortical tau accumulation and cognitive decline in preclinical Alzheimer’s disease

Study in peopleMechanisms

AAIC 2025 Abstract23 Dec

Apolipoprotein E (ApoE) 4 exacerbates pattern separation deficits and amyloid pathology in a combined humanized knock‐in Apolipoprotein E, Amyloid, and Tau model of Alzheimer's Disease

Experiments in animalsMechanisms

AAIC 2025 Abstract23 Dec

Hippocampal Amyloid‐Beta And Tau Distributions Differentially Affect Cognition In Centenarians

Study in peopleMechanisms