Hematopoietic stem and progenitor cells

Biomarker

2 papers study it139 more mention it1 finding

  • Humans1
  • Animals1

Associations

1

Frailty index

downin humans1

1 study
  1. Frailty index is associated with hematopoietic stem and progenitor cells in humans.

    “Reduced levels of circulating HSPCs and increased S100A8/A9 concentrations were independently associated with the frailty index.”

    Humansn = 104

    Hematopoietic progenitor cell liabilities and alarmins S100A8/A9-related inflammaging associate with frailty and predict poor cardiovascular outcomes in older adults

    Aging cell

More on Frailty index

Funding

3 grants since 2018

National Institute of Diabetes and Digestive and Kidney DiseasesUS$707.7kNational Heart, Lung, and Blood InstituteUS$494.2k

Latest

Nov 2025: 1Dec 2025: 3Jan 2026: 4Feb 2026: 2Mar 2026: 0Apr 2026: 3May 2026: 2Jun 2026: 5Jul 2026: 3Aug 2026: 6Sep 2026: 3Oct 2026: 436 papers in 12 months
Nature Communications

Cancer-promoting signals and immunity shape cell clearance in mice

In mice given altered blood-forming cells, cancer-promoting signals and immune defenses jointly shaped whether those cells were cleared.In mice given altered blood-forming cells, cancer-promoting signals and immune defenses jointly shaped whether those cells were cleared.

bioRxiv

DNA marks in King penguin blood may record stem-cell aging

An observational analysis of 126 whole-blood DNA profiles identified 409 genes with age-linked changes in chemical marks throughout life.An observational analysis of 126 whole-blood DNA profiles identified 409 genes with age-linked changes in chemical marks throughout life.

Preprint: experiments in animalsBiomarkers
Biogerontology

A metabolic protein promotes blood stem cell aging in mice

In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.

Experiments in miceMechanisms