Haemoglobin A1c

1. Hormone replacement therapy decreases haemoglobin A1c in humans (MD -5.47 mmol/mol (-0.50%)).

   “haemoglobin A1c (17 studies: N=15,720, MD -5.47 mmol/mol [-0.50%] [95% CI -8.32, -2.62 mmol/mol (-0.76, -0.24%)]”

   Reviewwomen with type 2 diabetesfemalesn = 15,720

   Menopause hormone therapy and type 2 diabetes risk and prognosis: systematic review and meta-analyses

   Diabetologia·18 Sep 2026

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1. Red cell distribution width is associated with haemoglobin A1c in humans (0.10% per 1 SD increase in RDW).

   “RDW was significantly and positively associated with HbA1c, corresponding an increase in HbA1c of 0.10% per 1 SD increase in RDW.”

   Humansn = 4,845

   Red cell distribution width, haemoglobin A1c and incidence of diabetes mellitus

   Journal of internal medicine·28 Jan 2014

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