Advanced Science
Serine shortage promotes a nondividing state in spinal disc cells
Laboratory experiments found that reducing serine, a building block of proteins, also reduced production of the structural material surrounding spinal disc cells.Laboratory experiments found that reducing serine, a building block of proteins, also reduced production of the structural material surrounding spinal disc cells.
Animal cell studyInterventions
Who was studiedRat nucleus pulposus cells, 72 h, against cells in normal medium
What changedSerine-deprived rat disc cells showed more signs of senescence than cells in normal medium
The catchSerine concentrations used in culture may not reflect physiological levels