Global cognition
Biomarker8 papers4 findings
- Human trial1
- Humans7
Upstream
3Osteoporosis
downin humans1
1 study
Osteoporosis
downin humans1
Osteoporosis impairs global cognition in humans (β = −0.033 per year).
Humanspost-onset follow-up17 yearsn = 6,496
Cognitive Trajectories Before and After Osteoporosis Onset: Evidence from a 17-Year UK · Research Square · 3 Sep 2026 · Preprint
Total brain volume
mediatesin humans1
1 study
Total brain volume
mediatesin humans1
Total brain volume mediates global cognition in humans (9%; β = 0.005, SE = 0.011).
Humansmediating the MIND diet associationbrainn = 713
MIND diet, cerebrovascular health, and cognition among community-dwelling older adults · Alzheimer's & dementia : the journal of the Alzheimer's Association · 1 Aug 2026
Arteriolosclerosis score
mediatesin humans1
1 study
Arteriolosclerosis score
mediatesin humans1
Arteriolosclerosis score mediates global cognition in humans (8.5%; β = 0.0048, SE = 0.002).
Humansmediating the MIND diet associationbrainn = 713
MIND diet, cerebrovascular health, and cognition among community-dwelling older adults · Alzheimer's & dementia : the journal of the Alzheimer's Association · 1 Aug 2026
Associations
1Mind diet
upin humans1Low certainty
1 study
Mind diet
upin humans1Low certainty
Mind diet is associated with global cognition in humans (β = 0.0506, SE = 0.011).
Humansbrainn = 713
MIND diet, cerebrovascular health, and cognition among community-dwelling older adults · Alzheimer's & dementia : the journal of the Alzheimer's Association · 1 Aug 2026
Latest
329Blood sugar swings linked to poorer thinking in some adults
Among adults with high blood pressure, greater blood sugar variability was linked to a 0.12 lower combined thinking-test score, comparing the highest…Among adults with high blood pressure, greater blood sugar variability was linked to a 0.12 lower combined thinking-test score, comparing the highest and lowest thirds.
APOE4 allele modifies the effect of lifestyle interventions on cognition
High neutrophil-to-lymphocyte ratio predicts cognitive decline
During five years of follow-up, 42.55% of older adults with high ratios progressed to mild cognitive impairment or dementia compared with 30.82% with…During five years of follow-up, 42.55% of older adults with high ratios progressed to mild cognitive impairment or dementia compared with 30.82% with normal ratios.