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Environmental Health Perspectives

Childhood mental activities linked to less lead harm in later life

In adults with less childhood stimulation, 1 part per million higher second-trimester lead was linked to 0.34 standard deviations lower cognitive scores, but not with…In adults with less childhood stimulation, 1 part per million higher second-trimester lead was linked to 0.34 standard deviations lower cognitive scores, but not with high stimulation.

Cohort study of 704 peoplePopulations
Psychology, Health & Medicine

Daily activity patterns alter cognitive links to widowhood

In 4,427 older Chinese adults followed across three survey waves, lower cognitive function linked to widowhood occurred primarily in passive and television-dominant…In 4,427 older Chinese adults followed across three survey waves, lower cognitive function linked to widowhood occurred primarily in passive and television-dominant sedentary activity patterns.

Cohort study of 4,427 peoplePopulations
HGG Advances

Summary-level genetic method improves Alzheimer's risk prediction

The endoPRS-SS framework boosted computational efficiency up to 90-fold while using summary statistics and multiple endophenotypes to improve Alzheimer's disease risk…The endoPRS-SS framework boosted computational efficiency up to 90-fold while using summary statistics and multiple endophenotypes to improve Alzheimer's disease risk prediction.

Computational studyAlzheimer's disease